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adaptive build clinical continuous designs information natural possible updating using
Using the Bayesian approach, it is natural to do continuous updating as information accrues. This characteristic makes it possible for us to build adaptive designs in clinical trials. Donald Berry
adaptive close faint found images optics parent produce seen sharp star using
Only by using adaptive optics to produce very sharp images could we have found this companion. It is too faint and too close to its parent star to be seen otherwise. Michael Liu
adaptive available broad consumers continuum deployed factors financial form full leading protecting proud proven range rather security single solution source uniquely via
Today, RSA Security is proud to unveil a solution that uniquely addresses the full continuum of financial institutions' authentication needs: the combination of risk-based and one-time password-based authentication -- and a broad range of form factors for two-factor authentication -- are available from a single source rather than via a hodgepodge of partnerships. Moreover, RSA Adaptive Authentication is live and proven today, with its modules already deployed and protecting consumers at many of the world's leading financial institutions. Chris Young
adaptive changing essential families form lay novelty raise social
Novelty is adaptive when things are changing and you need to adapt yourself. Tradition is essential to lay down the stability to raise families and form cohesive social groups. Tim Jackson
adaptive alone anxious capacity certain modern offer work
In the modern world, the anxious temperament does offer certain benefits: caution, introspection, the capacity to work alone. These can be adaptive qualities. Robin Marantz Henig
adaptive army bring company consumers far market seen
What we have seen is that our army of entrepreneurs, our users, bring to market what consumers want, and they are far more adaptive and prescient that any company can be, Meg Whitman
adaptive basically exchange goal rate stable
Our goal is to keep the exchange rate basically stable at adaptive and equilibrium levels. Hu Jintao
adaptive calls education hooked jeff phone physical teacher
We made some phone calls and e-mails back and forth. They hooked us up with Jeff Hendricks (an adaptive physical education teacher at Douglas) and we went from there. Ed Bronsdon
adaptive company consistent customer customers drive enable facing flexible industry laying loyalty processes provided repeat represent responsive solutions users vision
Siebel has provided a consistent vision for the CRM industry for over a decade. With Customer Adaptive Solutions -- and everything they represent -- the company is laying out a new vision for customer facing applications that are more flexible and better able to accommodate customer input. This will enable Siebel users to be more responsive to customers and enable the kind of customer centric processes that drive loyalty and, ultimately, repeat business. Denis Pombriant
artificial cool deals definitely society
It's going to be interesting to see how society deals with artificial intelligence, but it will definitely be cool. Colin Angle
artificial environment good work
We always want to live in an environment where there's no artificial block to good work. Chiwetel Ejiofor
artificial integrity sports
A sport has its own built-in integrity - doesn't need an artificial one. Chris Crutcher
artificial time totally
I think there is a little magic in the fact that I'm so totally real but look so artificial at the same time. Dolly Parton
artificial benefit bottom care cost few giving great helping line paying people pregnant publicly screening stop until women
The bottom line is, until we're helping people to stop smoking, screening for breast cancer, giving Pap smears, giving prenatal care to pregnant women, we should not go into publicly paying for the artificial heart, which will benefit at great cost only a few people. Richard Lamm
artificial genuine together
I am a fraud. I have cobbled together my personality from hundreds of little bits. I am simultaneously the most genuine and the most artificial person you will ever meet. Sebastian Horsley
artificial became computer founding intelligence mit moved science stanford
I moved to MIT from Stanford in 1984 to teach, and became the founding director of MIT's Computer Science and Artificial Intelligence Lab. Rodney Brooks
artificial ask businesses created executive
We have to ask ourselves, 'What kind of world is it where a baby-food executive substitutes artificial flavoring and sugar for apple juice? What kind of businesses have we created when we even lie to infants?' Paul Hawken
artificial fact intelligence majority planet
Most of the intelligence out there must be artificial intelligence. We keep looking for critters like us living on a planet like ours, where in fact the majority of the intelligence out there is not biological. That would be my argument. Seth Shostak
behavior extent looking
The Pentagon is looking into them. To the extent that kind of behavior is inconsistent with our policy, it will be stopped. Stephen Hadley
behavioral breadth complexity create face genetics include network novelty problems reflect science social time
It is time to create new social science departments that reflect the breadth and complexity of the problems we face as well as the novelty of 21st-century science. These would include departments of biosocial science, network science, neuroeconomics, behavioral genetics and computational social science. Nicholas A. Christakis
behavior direction far great mindless opportunity work
As far as One Direction goes, and Mindless Behavior and all the other bands, I'm all for it, and if there's ever an opportunity to work with them, that'd be great. Nick Jonas
behavior belief small
The abdication of belief makes the behavior small -- better an ignis fatuus than no illume at all. Emily Dickinson
behavior randomly stop test work
The assumption, I guess, that propels this is that once you randomly test students, they'll just stop experimenting. But behavior is really complex. It doesn't always work that simply. Jennifer Kern
behavior difference issues legitimate life talk whether wrong
There is a difference between legitimate issues of character - someone's behavior - and the issue of whether someone who has done something wrong in their life, now because of those mistakes, can't talk about what is the right thing to do. Rick Santorum
behavior impact people
We have to look at the impact of this kind of behavior on impressionable young people and if there is evidence, something should be done about it, Ian Blair
behavior impact
We have to look at the impact of this kind of behavior, and if there is evidence, something should be done about it. Ian Blair
behavior conduct falsehoods people truths vulgarity
Vulgarity is the conduct of other people, just as falsehoods are the truths of other people Oscar Wilde
cannot carry clean coffee cup fact guys help pilots planes running secretary
The pilots cannot get over the fact that I have a cup of coffee with the guys who carry the bags. My secretary will (even) go out and help clean the planes if we are running into a delay. Tony Fernandes
cannot clearly correction data dollar downward driven fed near outlook policy term
The outlook for the Fed policy is clearly data dependent. I cannot see much downward correction to the U.S. dollar over the near term being driven by the data. John Kyriakopoulos
cannot children
Parents cannot be in the same physical space as their children at all times. Beeban Kidron
cannot channel crossing invader narrow since succeeded
The English Channel is such a narrow little puddle, you cannot help wondering why no invader has succeeded in crossing it since 1066. David Hewson
cannot measurable science tendency
I think there is a tendency in science to measure what is measurable and to decide that what you cannot measure must be uninteresting. Donald Norman
cannot country creating government solve
You cannot solve the economy in this country by creating government jobs. Don Young
cannot
You cannot see the changes that you're dreaming about, because they're internal. Alice Walker
cannot war
I'm very disappointed in Obama. I was very much in support of him in the beginning, but I cannot support war. I cannot support droning. I cannot support capitulating to the banks. Alice Walker
cannot great lincoln
I cannot swallow whole the view of Lincoln as the Great Emancipator. Barack Obama
economics economy-and-economics
U.S. History, World History, Geography, Law, Economics and Psychology. Al Smith
economics europe exports oriented reduce says supply surplus textbook toward
We have overfed Europe with oil. Every economics textbook says that surplus supply lowers prices. But we can't reduce supply -- all our exports are oriented toward Europe. Semyon Vainshtok
economics headed hungry leadership led people programs younger
I think people are hungry for new ideas and leadership in the world of poverty alleviation. Most development programs are started and led by people with Ph.Ds in economics or policy. Samasource is part of a cadre of younger organizations headed by entrepreneurs from non-traditional backgrounds. Leila Janah
economics economy-and-economics learn mass produce
You learn about economics and mass produce little things to make a profit. Andrew Shields
economics major work
His work is important and a major contribution to the world of economics and to theory, Menachem Begin
economics taxes
Whatever you tax you get less of. Alan Greenspan
economics issue last margins number primarily problem profit reduction vaccines
The problem with vaccines is not a new problem, ... For the last decade, we have had reduction in the number of vaccine manufacturers. ...The issue comes down primarily to economics ... Profit margins are small. Mitchell Cohen
economics efficiency economy
There can be economy only where there is efficiency. Benjamin Disraeli
economics hundred labor
A hundred times every day I remind myself that my inner and outer life are based on the labors of others. Albert Einstein
economy-and-economics pilots qualified
The pilots are responsible, realistic, qualified people, who know the (state of the) economy, Jean-Cyril Spinetta
economy-and-economics supportive
Most are supportive before they look at the economics. Brian Wilson
economy-and-economics education health highly home physical teachers
It doesn't look like you need physical education teachers to be highly qualified. Or health or home economics. Nate Mackinnon
economy-and-economics remake singapore totally
We have to remake Singapore. Our economy, our education, our mind-set, our city. It must be a totally different Singapore. Because if its the same Singapore today, we're dead, Lee Loong
economy-and-economics good headlines
We don't get all the headlines up here, but it's a good economy. Jim Shabi
economy-and-economics india pivotal role
Positioned as we are, geographically and economically, India has a pivotal role in the region, Manmohan Singh
economy-and-economics obvious sees strong testimony tone
From the tone of his testimony today, it's obvious he sees a pretty strong economy. Daniel Jester
economy-and-economics emerging good markets relatively shape
Fortunately, most emerging markets are in relatively good shape economically. Paul Hansen
economy-and-economics home improvement instead investing last less market months people secure seen slow spending stock strong wake
Historically we have seen strong home improvement spending in the wake of a slow economy. The stock market has been less secure in the last 18 months or so than it had previously been. So instead of the stock market, people were investing in their homes. Chris Ahearn
exactly father quite suppose turned
I suppose I often think of my writing as quite impersonal. But it turned out, when my father died, writing was exactly what I wanted to do. Zadie Smith
exactly great literally people seem sort whenever
Some people seem to sort of have a gut for hiring. I literally had a gut that was exactly the opposite. So whenever I thought someone would be great, it was sort of the opposite. Wendy Kopp
exactly identified maybe people pinpoint
Maybe every city has a unique sensibility, but we don't have names for what they are or haven't identified them all. We can't pinpoint exactly what makes each city's people unique yet. David Byrne
exactly okay women
Women need to hear the words, 'It's okay if things don't go exactly the way you want them to.' Give yourself a break! Brooke Burke
exact experience material smile somebody though watching
When you're watching somebody read your material and they smile and nod, you know you've found that place where your experience and their experience match, even though they aren't the same exact experience. Chris Crutcher
exactly home people
Writers, particularly poets, always feel exiled in some way - people who don't exactly feel at home, so they try to find a home in language. Natasha Trethewey
exactly learnt until
Exactly the same with dancing, you can't dance until you've learnt steps, the things your feet can do. Ninette de Valois
exactly tough
That was the only blight on the game. It was a good, tough hit-out. We got out of it exactly what we wanted to get out of it. Steve McNamara
exactly hit needed picked point somebody step theresa
That was the hit that really got us going. When Theresa hit that homer, it picked everyone up. That was exactly what we needed at that point of the game. We needed somebody to step up and Theresa did just that. Scott Graf
influenced tremendous visceral
'Amores Perros' and 'Once Were Warriors' had a tremendous visceral quality that really influenced me. Brendan Fletcher
influenced looking period time
In comedy, looking back is more important than looking around at your contemporaries because they are too much influenced by the same time period as you are. David Steinberg
influenced music people
People have told me that other artists have been influenced by my music, and it's flattering. It's a wonderful thing. Roger McGuinn
influenced sound yes
I was so influenced by Yes then that things started to sound very much like Yes. Billy Sherwood
influenced naive taught
I would be naive to think that it's not going to be heavily influenced by a lot of things he's taught me. E. P. Thompson
influenced inherently literally movies setting videogames
Because videogames are so inherently influenced by movies, to take a movie and literally create a videogame out of it, you're immediately setting limitations and expectations on what that game can be. Josh Trank
influenced match referee
I don't think it influenced the game, but the referee should have started the match without them. Bryan Robson
influenced music
Where I've been hasn't influenced my music. It's more what I listen to. You can find music everywhere, so moving hasn't really influenced my music, more me as a person. Lykke Li
influenced watch
I used to watch my mother cooking when I was a child; she influenced me a lot. Nobu Matsuhisa
larger life love meaning people song specific successful
That's what I love about songwriting - that you can write something about your own experiences and think it's completely specific to you, and then people can take away a completely different meaning for themselves. I really love that. I think you've been successful at writing a song when it has a larger life than yourself. Idina Menzel
larger odd
The odd thing about comedy is that the more personal you are, the larger the audience. David Steinberg
larger-than-life has-beens uncompromising
I have been uncompromising, peppery, intractable, monomaniacal, tactless, volatile, and oftentimes disagreeable... I suppose I'm larger than life. Bette Davis
larger lying skeletons top
We have two skeletons preserved, the larger lying on top of the other one. James Clarke
larger market microsoft success tremendous
Microsoft had tremendous success with larger businesses, but that market has become very saturated. Joe Wilcox
larger parts
We have one of the larger parts to cover. Rease Watson
larger role
You'll always want to find an actor in the larger role first. Rebecca Mangieri
larger problem
The problem was much larger than we expected. Cassandra Dunn
larger picked pieces
little pieces being picked out of a larger context. Richard Boucher
limits teach capability
There's only so much you can teach a person until you reach the limits of his capabilities. Arnold Rothstein
limits faces competitors
Now to explore the limits of the one competitor above everyone else you've always loved to face: Steve Prefontaine. Bill Bowerman
limits
Nobody is going to put a limit on what I'm doing. Michael Phelps
limits player role
He's a role player on our team, but I think sometimes he limits his role more than he should. Bob Thomason
limits positive pushing return spur terms
His return is a big positive for the industry. It will spur everyone on, especially in terms of pushing the limits of technology, Jim Silver
limits accepting persons
Learn to accept your limits and you'll become a happier person. David D. Burns
limits worst ability
We must never limit God's ability to turn even the worst, most vile experience in our lives into something productive, beneficial and positive. Charles Stanley
limits stills hard
I still find it hard to push my own limits. I know where my limits are and that I always have to push myself. Charlotte Gainsbourg
limits variation levels
Whenever the current of money is forcibly stopped, and when money is prevented from settling at its just level, there are no limits to the possible variations of the exchange. David Ricardo
matter might novels
I write novels with a lawyer as the hero, no matter how oxymoronic that might sound. William Lashner
matters solid
The only ranking that really matters to us is how we feel about this class, and we feel like we have another good, solid class. Dennis Franchione
matter means past until
The past means nothing. It really doesn't matter until you get out there and play. Adrian Moss
matter past successful tomorrow
The past is the past, no matter how successful it's been. For me, it's only tomorrow that's interesting. Simon Cowell
matter mentality musician performer songwriter tried
The one mentality I've always tried to have is that no matter what stage in your career that you are in as a musician or a performer or a songwriter or whatever, there's always more to learn. Nick Jonas
matter natural superiors
Everything except God has some natural superior; everything except unformed matter has some natural inferior. C. S. Lewis
matter take-your-time
Stop and take your time to notice things and make those things you notice matter. Cecelia Ahern
matter three minutes
In three minutes, 98 percent of all the matter there is or will ever be has been produced. We have a universe Bill Bryson
matter orthodoxy may
Orthodoxy is the grave of intelligence, no matter what orthodoxy it may be. Bertrand Russell
problems
The anticipation would have been that problems would have been down. Tom Smith
problems
We have had so many problems in our district. Mark Harmsen
problems technical
We have had problems ? some serious, some not so serious. They were the logistical and technical problems we expected. Tom Leach
problems weather
Why would you put all your C-130s in a place with weather problems? Hilary Clinton
problems run share values win
You'll run into problems where governments don't share those values. Long term, these values will win out. David Filo
problems team
The problems were all over the field. The team has to get through 11 people. Eddie Pope
problems severe
The problems are more severe than they thought. John McMillan
problems team
The problems were all over the field, ... The team has to get through 11 people. Eddie Pope
problems seeing start
Unfortunately, that's when you'll start seeing problems with a lot of the grasses. Jim Clarke
reaches
You always dream of being part of a show that reaches and thrills an audience. Nikolaj Coster-Waldau
reach together
We're uniting together to reach out into the community. Sandra Williams
reach received
We have not received any offer. They know how to reach us. Bruce Teitelbaum
reached
I feel we reached out and stole a Clipper. Larry Harris
reach
He just said he tried. (He) just couldn't reach his girls. It's just sad. Debra Moore
reached
He immediately reached out to us. We're very grateful. Drew Kesse
reach struggle stuff
When you struggle to reach for something you don't know, that's where the most interesting stuff is. Herbie Hancock
reaches whose
My heart reaches out to those whose loved ones were lost on MH17. Najib Razak
reached
I want to be able to say on my deathbed that I reached a few people. That would be very nice, just to be able to say that. Evelyn Glennie
shown using
Using these extracts has been shown to work, Peter Sorensen
shown sustain
You have shown that one can sustain success. Amitabh Bachchan
shown
He just didn't show up and he still hasn't shown up. Gail Begley
shown
Had they not have shown up, it could have been tragic. Scott Hoffman
shown tonight
He has shown us little glimpses here and there, and I told him tonight he had to be better than the other goaltender, and he was. Jim Riccitelli
shown
He has shown me a lot. He's going to be an outstanding player. Larry Coker
shown
He doesn't have to show more. I like what he's shown already. He has to show more of the same. Dusty Baker
shown
We want them and I think we have shown you that. Rick Taylor
shown year
We're not a one-trick pony. We've shown it all year that we're not a one-trick pony. Ken Hitchcock
simply zealand
You simply couldn't make a living as an author if New Zealand was your only market. Paul Cleave
simply
We were simply brushed off by MAF officials. Peter Berg
simply
I'm simply a businessman who has seen his share of failures and successes. Jack Whittaker
simply time war
War at this time and in this place is unwelcome, unwise, and simply wrong. Martin Sheen
simply
He is simply exceptional. He is always there at exceptional moments. Patrick Vieira
simply talk
I don't just want to talk about goals. I know we can get there. We simply can't wait. Becky Lourey
simply
I can tell you that simply did not happen. Jim Wilkinson
simply slim small
But my eyes were riveted on a small slim woman her hair simply coiled into her neck, Katherine Glasier. Ellen Wilkinson
simply
Make your creed simply and broadly out of the revelation of God, and you will keep it to the end. Phillips Brooks
solutions
I really don't have any solutions and I don't like movies that do. Charlie Kaufman
solutions
I'd like to be an inventor, as they look at the world in a different way and find solutions for making it better. Neil Jackson
solutions updated users
Most U.S. users updated their anti-virus solutions because of Melissa, so they are safe. Sal Viveros
solutions trying
You think about a lot of situations. That's just part of coaching. You're trying to find solutions every day. We haven't had enough of them in the playoffs. Dave Tippett
solutions
We are very short on organs, and the pig solution is probably a lot better than the human clone solution - though maybe not for the pigs. Margaret Atwood
solutions
Angela Merkel is the best solution for Poland. Jaroslaw Kaczynski
solutions writer writers-and-writing
A writer is a person who has solutions for which there are no riddles. Gregory Nunn
solutions
Point at solutions instead of at each other. Jeffrey Pfeffer
solutions
To stay back from an intervention is not always a good solution. Paul Wolfowitz
strongly
I strongly feel that we are all connected, Gloria Estefan
strongly
I feel very strongly that we are in the driver's seat. John Gandy
strongly
I feel very strongly that that's not where we should be going with this, Jim Doyle
strongly vote
He should be strongly considered, 13 wins, 200-plus innings. I'd vote for him. John Gibbons
strongly
I don't feel as strongly as I did before on that. Basically, I shouldn't have made that comment. Brad Cashman
strongly
I feel strongly he'll be able to play somewhere. Lloyd Church
strongly suggest
We strongly suggest that he does not do that, Endriartono Sutarto
strongly
We're a strongly capitalised bank, after this loss, by international standards, Michael Buckley
strongly three win
I think we win three for sure. Everything is trending strongly our way. Rob Stutzman
system using work
We have all new duct work and a new heating and ventilation system in there, so we won't be using the old system, Chuck Wilson
system
We have to have a system for response. Bob Ray
systems weather
Fortunately, the weather did end up cooperating, and it's all systems go. Mike Claffey
system
We've got to have just one system . . . it's a no-brainer. Lance Lyttle
system talking
There is no new system in place. I don't know what you're talking about. Bill Belichick
system
We're still making improvements to the system and assessing it, but everything is being done with long-term use in mind. Jennifer Post
system word
We feel that the system will get the word out when it's needed. Kevin Potter
systematic mental-illness institutions
The family unit is the institution for the systematic production of mental illness. Ashley Montagu
system weakness
There is a weakness in the system somewhere, David Hayes
wants
What mankind wants is not talent; it is purpose. Edward G. Bulwer-Lytton
wants
I'm not one of those guys who wants to die on a stage. Don Rickles
wants wherever whoever
Wherever or whoever wants to do that, let's do it. Pervez Musharraf
wants
It is exciting. It is something everyone wants to be a part of. Kristy Gaudiose
wants
Poverty wants some, luxury many, and avarice all things. Lucius Annaeus Seneca
wants
We're all just kind of in the groove. And no one wants to get off anything right now. Shaun Alexander
wants worries worry
I don't think Shaq really worries about it. I think he wants to play well, but he doesn't really worry about it. ... It's over. Gary Payton
wants whoever
For whoever wants to come, we're going to be here for them. Victor Rodriguez
wants
He's got to look at what he wants to do. Brian Billick
within
We have very well-trained RAs and RDs within residence halls, Gary Thompson
within
Typically within two weeks, we're done with the analysis. Kerry Bailey
within work
We have to learn how to work within the limits that are possible, not what is desirable. Roberto Azevedo
within
I would say it's more within my expectations. Nizam Idris
within
We're number-crunching to see what we can do within our mandate. Michael Mann
within
It?s just an unbelievable experience. To come into it and have no idea where you?re going to go and find out within minutes, I think it?s really exciting. I can?t wait. Ann Strother
within work
We will have to work within the budget. Jeremy Duxbury
within worry
What I worry about is a new fiefdom within an already big fiefdom, Bill Richardson
within work
We work within the system. I don't want to say we're rebellious. Jeffrey Smith