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advanced anticipate approval attention believe candidates compound continue deficit develop disorder fda filing future half lead looking performance pipeline plan pleased positions products progress quarter receiving research second together treatment year
We are pleased with our performance in 2005. The year was highlighted by the filing of the new drug application on NRP104, our lead compound under development, for the treatment of Attention Deficit Hyperactivity Disorder in pediatric populations. We believe that this advancement together with the progress on our other pipeline products positions us well for future growth. Looking forward, we anticipate receiving approval from the FDA on NRP104 in the second half of 2006 and making IND filings on NRP409 and NRP388, the two most advanced candidates in our preclinical pipeline, by the end of the second quarter of 2006. In addition, we plan to continue to develop NRP290, our second most advanced compound, and other drug products in our research pipeline. Krish Krishnan
advanced base broad continuing economics formal gain knowledge latter political reasonable science self skills symbolic together
By a combination of formal training and self study, the latter continuing systematically well into the 1940s, I was able to gain a broad base of knowledge in economics and political science, together with reasonable skills in advanced mathematics, symbolic logic, and mathematical statistics. Herbert A. Simon
advanced challenges countries industrial question rise today
There is no more important question for advanced industrial countries today than how to rise to the challenges and opportunities of globalization. Gordon Brown
advanced aggressive business companies corporate documents manage print providing realized since site tool web
We've always had an aggressive e-commerce strategy. Since our first Web site in 1994, we realized a Web site was more than just a corporate brochure. It had to be an advanced business tool providing everything companies need to design, print and manage their documents online. Dan Beck
advanced deliver four networks six smarter technology
With today's advanced technology, ad networks can be a lot smarter about how they deliver ad impressions than they were four to six years ago. Rich LeFurgy
advanced along approach architecture balanced business core customer data delivered earnings geographic key order per pleased proves results revenue second share solid strategy strong technology terms video
We're pleased with the solid revenue and earnings per share results Cisco delivered during its second quarter, but also especially pleased with our strong order momentum. This proves our strategy is working in terms of the convergence of voice, video and data along with our balanced approach to our customer segments, core and advanced technologies, business and technology architecture and key geographic theaters. John Chambers
advanced highly motivated
We're a well-trained organization, highly disciplined and highly motivated .. very technologically advanced here, Peter Ryan
advanced began people popular understand
Over the years, I began to understand that there were a lot of people out there reading physics in popular literature that they could not understand - not because it was too advanced, but because it wasn't advanced enough. Leonard Susskind
advanced pushed rate sales success terms
With these advanced capabilities, we see our success rate in terms of new and follow-up sales being pushed through the roof. Nigel Kelly
center cook inside knows played position
We always have Cook that's there, that's played center, that knows the center position inside and out. Jeff Stoutland
centers disease except facility fact highly locked remarkable scourge secure similarly stored thousands tiny vanished vault
It is a remarkable fact that smallpox, a scourge for thousands of years, has now vanished from the earth, except for two tiny vials, one locked in a highly secure facility at the Centers for Disease Control, in Atlanta, and another stored in a similarly secure vault in Siberia. Michael Specter
center feelings
I don't have the feelings of self-worth that a woman should have... and that's been the center of a lot of my mistakes and a lot of my pain. Monica Lewinsky
center children coming emergency increase rising seeing
We are seeing a rising increase in children coming through our children's emergency center with injuries. Kathy Harper
center importance microsoft partners people presenting push research value
We started the push by presenting to partners the importance of people being at the center of how Microsoft delivers value in research and development and for customers. Allison Watson
centers clearly convention giving market space talking winners
We're talking about a market where convention centers are giving their space away. There clearly will be winners and losers. Heywood Sanders
center controls feet fit form game jon less midfield minute point solid source start steve takes
We start a lot form Tom's feet at center back. Stefan takes over at the midfield and controls things from that point on. He's more or less the distribution source for everything. And Jon and Steve are just really solid workhorses in the midfield. They could play in every minute of every game and through overtime. They're just real fit specimens. Don Haddox
center consider county crosses district downtown elected front hospital line mind money nearest notice plan putting sides texas trauma travel white
When you travel through Montgomery County and notice the white crosses on the sides of the roads, keep in mind that the nearest trauma center to each cross is downtown Houston. The 2007 Texas Legislature will consider appropriating money for more trauma centers. If elected to the hospital district board, I plan on putting Montgomery County at the front of the line for one of these new facilities. Jim Becka
centers death football four halftime others polling running taliban voting women
When you think four years ago Taliban were here, women were being stoned to death at halftime at football games, now you have women running polling centers and women voting and men voting and, I think, each one voting for some of the others as well. Ronald Neumann
four last match proved ways won
We've won one game. We won four last year. We've got a ways to go before we match last year. We haven't proved anything. J. Taylor
four influence borges
My influences have been what I call my four Bs - the primary one being the blues, then Borges, Baraka, and Bearden. August Wilson
four hard physical practice
We always get better in practice because we have four strong, physical guys. It's got to be real hard to play against. Adrian Moss
four asylums lasts
For me, stripping was an unusual kind of escape. I had nothing to escape but privilege, but I claimed asylum anyway. At twenty-four, it was my last chance to reject something and become nothing. I wanted to terrify myself. Mission accomplished. Diablo Cody
four guards looking plays using
UNLV plays four guards. So using four guards was something we were looking at doing anyway. Don Flanagan
four great last learn practicing
We are practicing with Hartland and they will get us prepared. They've been there the last four years and we should learn from them. They are a great program. B. F. Skinner
four larger whim
We started this on a whim four years ago. We don't want to make it any larger than it is. It really is a lot of fun. Jim McCann
four large plays shows
We are a fluid, but large group. We do a lot of plays and four shows a years. Caryn Jeffreys
fourth normally passive shots
We started getting passive in the fourth quarter. We didn't take some of the shots we normally take. Michael Teller
help willing
The one thing you will find between all of the employees, particularly the linemen, is that they are willing to go out and help when there is a need like this, Ken Miller
help people smoking somebody trying urge
The other thing is, when you see somebody smoking and you're trying to quit, you get that urge again. It doesn't help people quit, Richard Roberts
help inspire positive pursue
The positive thing about it is I can use my story to inspire other people, to help them see that they can do what they want to help them pursue their dreams. If I can help one person that would make me happy. Kevin Hall
help information memory online people providing resources
We are providing a lot of information and online resources to help people who have memory concerns. Anne Ward
helped offensive rushing transition
We started rushing things on the offensive end and that only helped them get into their transition game. Sarah Clapper
help latinos people rest
We want people to know Latinos help not only Latinos, but the rest of the people. Andres Perez
helping desperate help-me
I got to that desperate place where nobody could help me but God. Cheryl James
helping-others people want
A consultant solves other people"s problems. I could never do that. I want to help other people solve their own problems. Charles Handy
helping
Authentic faith cannot help but act. Beth Moore
management reflects worry
Worry in a CIO reflects uncertainty in the management process. Ed Moyle
management terrorism torture
Shamefully we now learn that Saddam's torture chambers reopened under new management, U.S. management. Edward Kennedy
management sole folly
Anger and folly walk cheek by sole. Benjamin Franklin
management total
At around 80 percent, it effectively has total management control. Mikir Shah
management proposing quite
They have a right to be upset, because what management is proposing is quite dramatic. Vaughn Cordle
management
This does not have the earmarks of a long-planned management transition. Carol Levenson
management poised reason seem strong team uphill
It's an uphill battle, but they seem poised to be able to do it. And the reason I say that is they have a strong management team in place. Sam Bhavnani
management northwest pilots tendency
Northwest management has a tendency to misjudge the will of the pilots group. Will Holman
management needed
Things that needed to get done, the management has done. Larry Haverty
networking building-wealth essentials
Networking is an essential part of building wealth. Armstrong Williams
network shifting social word
Where I do my word processing, how I collaborate, maintaining my social network . . . those things are shifting away from Microsoft. Tom Bittman
networks night roll strong thursday winning
They need Thursday to be their strong night, ... Thursday was such a strong night for them so long that they used to get by without winning any other night of the week. The other networks used to roll over. Shari Brill
network night television week
It's the loneliest night of the week for network television and television in general. Mitch Metcalf
networking overly
There's a way to do networking that isn't overly brown-nosing. Jill Abramson
networking social utilize
I really utilize all of my social networking sites. Bethany Mota
networks people saw turned
People thought I was an idiot, but I saw social networks were going to be more important, and it turned out to be true. Robert Scoble
network vulnerable
The most vulnerable part of the network are the undersea pipelines. E. B. White
network wireless
Now if you have a wireless network that won't connect, well, you need someone on-site. Chris Morris
operations
How do you feel the operations are going? George H. W. Bush
operations routine special turn
In a special operations mission, a routine mission, if you're detected on the way to the target, you may as well turn around and go home. You failed. William Patterson
operations sell shrink whatever
They'll have to shrink their operations and vigorously sell whatever they can. David Butler
operations
They have to completely revamp their operations to survive. Joseph Schwieterman
operations surplus
It makes our operations show that there's a big surplus when you don't have a big surplus. Dale Timmermann
operations ruling similar since
But since they have been a part of similar operations previously we are not ruling out the possibility. Ajay Singh
operations preparing since
We've been preparing for such operations ever since 2003. Hong Zhijian
operations
We think that cross-border operations would be unwise. E. O. Wilson
reduce vote
This is the only vote you will have to reduce the deficit. Judd Gregg
reduced reverse time yesterday
The thing yesterday for the first time in a long time was reduced risk-aversion...it was the reverse of the flight-to-quality. Michelle Laughlin
reduce understand
I understand the reactions, but it's not for me to reduce myself to that level. Agin Muhammad
reduce
This is not a new concern, but it is one we take seriously. We are working to reduce our vulnerability to this threat. Gordon Johndroe
reduce wasteful
As a taxpayer, I want to assure you that Republicans are doing everything we can to reduce wasteful spending. Jeff Miller
reduce risk striking
What is striking is that it didn't take much to reduce the risk ... If you don't exercise, you should start. It's never too late. Dr. Larson
reduce
With lab courses, we may be able to simulate a lot of that and reduce costs. Roy Romer
reduce thinking tried
We just tried to reduce our thinking before that first touchdown, let's just get one series. Karl Dorrell
reduced
I'd rather see the tax for innovation reduced rather than expanded. Mitt Romney
steps backing-up steady
History has spurts and then is steady, and then maybe even backing up a step, and then forward again. Alan Bean
steps comfort grows
It is only when You really STEP OUT of Your comfort zone that You GROW. Bear Grylls
steps problem illegal
Illegal immigrants are already a very big problem for us. We are already taking big steps to disallow illegal immigrants from coming in. Antonis Samaras
steps commencement experiments
One failed experiment is one step closer to Success Denzel Washington
steps should
Until we see what we are, we cannot take steps to become what we should be. Charlotte Perkins Gilman
steps tough push-yourself
You take yourself to a place where you've got absolutely nothing left and then you find out you have to push yourself one more step. That's a tough place to be in. Bryan Clay
steps team tonight
We play as a team and someone always steps up. Tonight it was just my time, my chance, to be there for the team and do that. Lisa Busch
steps action projects
You don't actually do a project; you can only do action steps related to it. David Allen
steps surprise reader
I really like it when you can step outside of what's come before and find a surprise for the reader and find a surprise for yourself. Dave Gibbons
systems terrible widespread
It would have been terrible (without the widespread patching). That got a lot of systems fixed. Alan Paller
systems weather
Fortunately, the weather did end up cooperating, and it's all systems go. Mike Claffey
systems-change belief circumstances
External circumstances will not change until internal belief systems change. Myles Munroe
systems
I think you'll see very aggressively priced systems out there. Paul Otellini
systems-change consciousness individual
As one individual changes, the system changes. Ram Dass
three four finished
In 1980 I finished three or four times in seventh place. Alain Prost
three balls easy
The three-ball is an easy shot if you're uncontested, but when they know you can shoot, it's a lot harder to get off. Chris Copeland
three
The other three have really made strides. They're consistently getting better. Bill Wright
three moments hours
Preferred three hours quicker over one moment late. William Shakespeare
three cinema use
When I started my first film, there were three women directors in France. Their films were OK, but I was different. It's like when you start to jump and you put the pole very high - you have to jump very high. I thought, I have to use cinema as a language. Agnes Varda
three essentials action
There are three essential factors in all human activity: spirit, materials, and action. Chiang Kai-shek
three purpose salvation
Purpose, and to be thoroughly wedded to that purpose, is three quarters of salvation. Charles Henry Parkhurst
three elements recognition
Recognition is one of the three big elements of comedy. Bill Maher
three males pubs
Three women walk into a pub and say, `Hooray, we've colonised a male-dominated joke format' Bill Bailey
time fool calendars
Tomorrow! It is a period nowhere to be found in all the registers of time, unless, perchance, in the fool's calendar. Charles Caleb Colton
time all-things
Time is the measurer of all things, but is itself immeasurable, and the grand discloser of all things, but is itself undisclosed. Charles Caleb Colton
time retreat tides
Time ... advances like the slowest tide, but retreats like the swiftest torrent. Charles Caleb Colton
time two black
Time,- that black and narrow isthmus between two eternities. Charles Caleb Colton
time looks one-thing
To look back to antiquity is one thing, to go back to it is another. Charles Caleb Colton
time world overcoming
Time is the most subtle yet the most insatiable of depredators, and by appearing to take nothing is permitted to take all; nor can it be satisfied until it has stolen the world from us, and us from the world. It constantly flies, yet overcomes all things by flight; and although it is the present ally, it will be the future conqueror of death. Charles Caleb Colton
time journey men
Much may be done in those little shreds and patches of time which every day produces, and which most men throw away. Charles Caleb Colton
time opportunity enemy
Time, the cradle of hope.... Wisdom walks before it, opportunity with it, and repentance behind it: he that has made it his friend will have little to fear from his enemies, but he that has made it his enemy will have little to hope from his friends. Charles Caleb Colton
time past gone
Time is the most undefinable yet paradoxical of things; the past is gone, the future is not come, and the present becomes the past, even while we attempt to define it. Charles Caleb Colton