Bruce Beutler
Bruce Beutler
Bruce Alan Beutleris an American immunologist and geneticist. Together with Jules A. Hoffmann, he received one-half of the 2011 Nobel Prize in Physiology or Medicine, for "their discoveries concerning the activation of innate immunity"...
NationalityAmerican
ProfessionScientist
Date of Birth29 December 1957
CountryUnited States of America
award effect family feels nicest received relationship though
The nicest part of the prize, perhaps, is the effect on my friends and family. Each of them feels proud and happy to have the relationship with me that they do. In a way, it's as though they received an award too, and I like that very much.
cases colossal complex disease environmental genetic immune maintain majority next react ready result system task
Autoimmunity is probably the next frontier. The majority of cases of autoimmune disease result from a complex genetic problem that has environmental influences. It is a colossal task for the immune system to maintain tolerance to self and yet be ready to react to everything in the world around us.
far immune
If we think of the immune system as a machine, then we are far from even knowing all of its parts.
people
If you really want to isolate a disease, then you have to isolate the people who carry it.
far highly science
Science is far from the center of the world for most people: even for many with highly sophisticated tastes, interests, and accomplishments.
create form found gene learn mouse phenomenon required saw seeing simply single trait
A mutation can create an alternative form of a phenomenon - a phenotype or trait - and we can learn a lot by seeing this alternative state. Once I saw a mouse with no eyelids. It simply had a membrane over the eyes. I found it fascinating that there is a single gene required for eyelids to develop.
chance chances enhance finding leads
Chance leads to discoveries, and mutagenesis is a way to enhance one's chances of finding a surprise. Often it is the exceptional observations that lead to advances; once you understand exceptions, you understand the whole picture.
people sure transmit variation
People may have said that without symptoms, you can't transmit Ebola. I'm not sure about that being 100 percent true. There's a lot of variation with viruses.