Eric Nestler
Eric Nestler
actions analysis level molecular points potential provides regions study treatments understand
Our study provides a fundamentally new level of analysis by which we can better understand the actions of cocaine in brain-reward regions at the molecular level. It also points to new potential treatments for addiction.
chronic cure easily elsewhere induced molecular perhaps remove scar stress treatments
The molecular scar induced by chronic stress in the hippocampus, and perhaps elsewhere in the brain, can't be easily reversed. To really cure depression, we probably need to find new treatments that can remove the silencer molecules.
brain changes chronic effects existing insight provides stress study triggers
Our study provides insight into how chronic stress triggers changes in the brain that are much more long-lived than the effects of existing antidepressants.
behavioral both removal treatment
Removal of BDNF before bullying, or treatment with antidepressants after bullying, both removed the behavioral abnormality observed.