Eugene Major
Eugene Major
Eugene O. "Gene" Major, PhD, is a senior investigator at the National Institute of Neurological Disorders and Stroke, a part of the United States National Institutes of Health. Major conducts research into the neurological diseases including progressive multifocal leukoencephalopathy, caused by JC virus and often found in immunosuppressed patients such as those with HIV/AIDS. Major has published over 140 scientific articles and reviews in the peer-reviewed literature and has contributed to Fields Virology, a standard virology textbook...
careful higher normal risk
Statistically then, the risk is approximately 1 in 1,000, which is substantially higher than in the normal population. We're also careful to say we do not know what the risk is for individuals with long-term use of the drug.
alter close effects immune might rare remains understand
Even under close evaluation, PML remains a rare disease. But as we alter the immune system, we need to understand what unintended effects it might have.
alter close effects immune might rare remains understand
Even under close evaluation, PML remains a rare disease. But as we alter the immune system, we need to understand what unintended effects it might have.
assess might
We had to assess who else might be at risk.
concluded evidence particular time
We concluded that at this particular time there is no evidence that there are more PML cases.
additional cases evidence found
We have found no evidence of additional cases of PML.