Eva Nogales
Eva Nogales
Eva Nogalesis a biophysicist at the Lawrence Berkeley National Laboratory. She is a faculty member in the Division of Biochemistry, Biophysics and Structural Biology of the Department of Molecular and Cell Biology at the University of California, Berkeley and a Howard Hughes Medical Institute investigator...
binding both cap common compare complexes cup factor interact mechanisms protein required site
What we were able to do is compare the binding site of both the viral RNA and the cells' cap binding protein on a factor that is common to both mechanisms in eIF3. The binding cap is one of the complexes required by the cell, but not required by the virus. For translations, this cup binding protein has to interact with the eIF3.