Karl Landsteiner
Karl Landsteiner
Karl Landsteiner, ForMemRS, was an Austrian biologist and physician. He is noted for having distinguished the main blood groups in 1900, having developed the modern system of classification of blood groups from his identification of the presence of agglutinins in the blood, and having identified, with Alexander S. Wiener, the Rhesus factor, in 1937, thus enabling physicians to transfuse blood without endangering the patient's life. . With Constantin Levaditi and Erwin Popper, he discovered the polio virus in 1909. He...
NationalityAustrian
ProfessionScientist
Date of Birth14 June 1868
CountryAustria
Karl Landsteiner quotes about
I have recently observed and stated that the serum of normal people is capable of clumping the red cells of other healthy individuals... As commonly expressed, it can be said that in these cases at least two different kinds of agglutinins exist, one kind in A, the other in B, both together in C. The cells are naturally insensitive to the agglutinins in their own serum.
On the whole, at least in the author's experience, the preparation of species-specific antiserum fractions and the differentiation of closely related species with precipitin sera for serum proteins does not succeed so regularly as with agglutinins and lysins for blood cells. This may be due to the fact that in the evolutional scale the proteins undergo continuous variations whereas cell antigens are subject to sudden changes not linked by intermediary stages.