Paul Rothemund
Paul Rothemund
Paul Wilhelm Karl Rothemund is a senior research fellow at the Computation and Neural Systems department at Caltech. He has become known in the fields of DNA nanotechnology and synthetic biology for his pioneering work with DNA origami. He shared both categories of the 2006 Feynman Prize in Nanotechnology with Erik Winfree for their work in creating DNA nanotubes, algorithmic molecular self-assembly of DNA tile structures, and their theoretical work on DNA computing. Rothemund is also a 2007 recipient of...
again change custom means natural short single staple strand synthesis time virtue virus
Another virtue of my experiments is that I use the same long single strand over and over again (the natural virus sequence) and I just change the ∼200 short staple strands. This means I don't have to do a custom long synthesis every time I want to make a new structure.
computer designed hands self
It self-assembles completely. It's all designed in the computer and then it's hands off.
case dna eyes faces fold holes leave shape
We actually fold the DNA into any shape that we want. So in the case of the smiley faces that I made, I actually fold the DNA into a disk, but then leave two holes for the eyes and the mouth.